Simplify to a single power of 4:

4^6/4^2

To simplify this expression, we can use the rule of exponents that states when you divide two powers with the same base, you subtract their exponents. In this case, we have 4^6 divided by 4^2.

4^6/4^2 = 4^(6-2) = 4^4

So the simplified expression is 4^4.