How did the arrival of Spanish explorers affect Native Americans?

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1 point
A. Spanish exploration brought settlers who pushed Native Americans north and out of Texas.
B. Native Americans and the Spanish became friends and established a practice of trading goods.
C. Conflict with the Spanish and the spread of disease killed many Native Americans.
D. Native Americans encouraged the Spanish to stay and settle in Texas.

C. Conflict with the Spanish and the spread of disease killed many Native Americans.