What is the timing between the swelling & thyrotoxic symptoms in graves disease? �
In Graves' disease, the timing between the swelling and thyrotoxic symptoms can vary. Generally, the onset of thyrotoxic symptoms occurs first, such as an increased heart rate, palpitations, weight loss, heat intolerance, and anxiety. These symptoms result from the excess production of thyroid hormones by the overactive thyroid gland.
Following the thyrotoxic symptoms, patients may start to experience swelling or enlargement of the thyroid gland. This swelling, known as a goiter, can cause a visible bulge in the neck area and may also be accompanied by difficulty swallowing or a feeling of pressure in the neck.
The time frame between the appearance of thyrotoxic symptoms and the development of a goiter can vary among individuals. For some, the goiter may be present at the time of diagnosis, while for others, it may develop gradually over weeks or months. Additionally, not all individuals with Graves' disease will develop a goiter.