Jo flips a coin {H, T}; then rolls a 6-sided die {1, 2, 3, 4, 5, 6}.

How many possible outcomes are in the sample space of this experiment?

There are 2 possible outcomes for flipping a coin (heads or tails) and 6 possible outcomes for rolling a die (numbers 1 to 6). Therefore, the total number of possible outcomes in the sample space of this experiment is 2 × 6 = 12.