A cell contains DNA damage that causes it to undergo apoptosis before reaching mitosis. This cell had twice the amount of DNA for a cell of this type. During which checkpoint did this cell trigger apoptosis?(1 point)
Responses
G1
Checkpoint
cap g sub 1 Checkpoint
G2
Checkpoint
cap g sub 2 Checkpoint
M
Checkpoint
cap m Checkpoint
No checkpoint meets these criteria.
No checkpoint meets these criteria.
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The correct answer is G2 Checkpoint.
In this case, the cell triggered apoptosis at the G2 checkpoint.
To determine during which checkpoint the cell with DNA damage triggered apoptosis, we need to understand the cell cycle checkpoints and their functions.
The G1 Checkpoint (also known as the restriction point) occurs at the end of the G1 phase. Its purpose is to ensure that the cell has a favorable environment, sufficient nutrients, and receives appropriate signals to proceed to the S phase and undergo DNA replication.
The G2 Checkpoint takes place at the end of the G2 phase, just before entering mitosis (M phase). It checks for DNA damage and ensures that DNA replication has occurred accurately during the S phase.
The M Checkpoint, also known as the spindle checkpoint or metaphase checkpoint, occurs at the end of the metaphase stage of mitosis. Its function is to ensure that all chromosomes are properly attached to the spindle fibers before the cell proceeds to anaphase.
Based on the information provided, the cell with DNA damage that had twice the amount of DNA for a normal cell triggered apoptosis before reaching mitosis. Therefore, the correct answer is "No checkpoint meets these criteria." None of the checkpoints (G1, G2, or M) are responsible for triggering apoptosis due to DNA damage. Apoptosis is usually initiated by specific pathways and molecular signals, such as p53 activation, which are not associated with the regular cell cycle checkpoints.