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Which of the following explains the impact of the creation of the smallpox vaccine on the Americas?(1 point)

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It led to the deaths of about 90 percent of Indigenous Americans.
It led to the deaths of about 90 percent of Indigenous Americans.

It led to the complete eradication of the disease.
It led to the complete eradication of the disease.

It led to the development of ways to prevent the disease like mosquito nets.
It led to the development of ways to prevent the disease like mosquito nets.

It prevented milkmaids on the two continents from getting the disease.
It prevented milkmaids on the two continents from getting the disease.

It prevented milkmaids on the two continents from getting the disease.

The impact of the creation of the smallpox vaccine on the Americas includes the following:

1. It led to the deaths of about 90 percent of Indigenous Americans.

2. It led to the complete eradication of the disease.

3. It led to the development of ways to prevent the disease like mosquito nets.

4. It prevented milkmaids on the two continents from getting the disease.

The correct answer is "It led to the deaths of about 90 percent of Indigenous Americans." The smallpox vaccine had a devastating impact on Indigenous Americans because they had no previous exposure to the disease and therefore had no immunity. When European colonizers brought smallpox to the Americas, it caused widespread outbreaks among Indigenous populations, resulting in high death tolls. To find the answer to this question, one would need to have knowledge of the history of smallpox and its impact on the Americas.