Which statement best analyzes a key difference between European expansion in the Western and Eastern hemispheres, one the Roman Catholic Church told the European nations they could explore the Eastern Hemisphere but only parts of the Western Hemisphere, two Europeans did not set up colonies in the Eastern hemisphere but Europeans did set up colonies in the Western Hemisphere, three in the Eastern hemisphere Europeans focused on conquering as many local people as they could while in the Western Hemisphere Europeans peacefully traded with local people or, four in the Eastern hemisphere Europeans were able to set up trade relationships with different people's but in the Western Hemisphere Europeans focused on conquering different people

The statement that best analyzes a key difference between European expansion in the Western and Eastern hemispheres is:

Four in the Eastern hemisphere Europeans were able to set up trade relationships with different people's but in the Western Hemisphere Europeans focused on conquering different people.

The statement that best analyzes a key difference between European expansion in the Western and Eastern hemispheres is option three: "In the Eastern hemisphere, Europeans focused on conquering as many local people as they could, while in the Western Hemisphere, Europeans peacefully traded with local people."