The drawing entitled Isabella d'Este was drawn by _____________________.

A.
Pablo Picasso
B.
Asher Brown Durand
C.
Leonardo da Vinci
D.
Francisco Succarelli

C. Leonardo da Vinci

To find the answer to the question, you can follow these steps:

1. Begin by searching for the drawing entitled "Isabella d'Este" on an internet search engine or an art database. You can use keywords such as "Isabella d'Este drawing" or "Isabella d'Este artist."

2. Look for reliable sources that provide information about the drawing and its artist. Art databases, museum websites, or books on art history could be useful in this case.

3. Examine the details of the drawing and compare it to the artistic style and characteristics of different artists. Look for any specific features or techniques that might help you identify the artist.

4. Based on the gathered information and analysis, select the artist that seems to match the description of the drawing. In this case, the options are Pablo Picasso, Asher Brown Durand, Leonardo da Vinci, and Francisco Succarelli.

In this specific instance, the correct answer is C. Leonardo da Vinci. He is well-known for his artistic talent and mastery, and he created numerous drawings, including one of Isabella d'Este.

C. Leonardo da Vinci