What is a reason that the Missouri Compromise did not have lasting effects?

• It only applied to the lands of the Louisiana Purchase.
• It only applied to the lands of the Mexican Cession.
• It relied on popular sovereignty.
• It limited the number of states that could be admitted per year.

The reason that the Missouri Compromise did not have lasting effects is that it only applied to the lands of the Louisiana Purchase. At the time, the United States was rapidly expanding, and new territories were being acquired through various means. As a result, the Missouri Compromise became obsolete as new territories were acquired, and it was no longer relevant. Additionally, the Compromise relied on popular sovereignty, which allowed each territory to determine its own position on slavery, which led to further tension and conflict over the issue of slavery in the territories.