Biology A Semester Exam
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Question
The mutation shown in the sequence below can be categorized as which type?
Original DNA sequence:
A T A C G G T A G C A A
T A T G C C A T C G T T
Mutated DNA sequence:
A T C G G T A G C A A
T A G C C A T C G A A(1 point)
Responses
deletion mutation
deletion mutation
substitution mutation
substitution mutation
chromosomal mutation
chromosomal mutation
insertion mutation
insertion mutation
To determine the type of mutation in the given DNA sequence, we need to compare it to the original DNA sequence and identify the changes that have occurred.
Original DNA sequence:
A T A C G G T A G C A A
T A T G C C A T C G T T
Mutated DNA sequence:
A T C G G T A G C A A
T A G C C A T C G A A
Now, let's analyze the changes:
1. Deletion mutation: This occurs when one or more nucleotides are removed from the DNA sequence. In the given mutation, there is no missing or deleted nucleotide.
2. Substitution mutation: This occurs when one nucleotide is replaced by a different nucleotide. In the given mutation, there are two substitutions: "A" is replaced by "C" in the first position and "G" is replaced by "A" in the last position.
3. Chromosomal mutation: Chromosomal mutations involve changes in the structure of the chromosomes. The given mutation does not involve any changes in the chromosome structure.
4. Insertion mutation: This occurs when one or more nucleotides are added to the DNA sequence. In the given mutation, there is no insertion of nucleotides.
Based on the analysis, the mutation shown in the sequence can be categorized as a "substitution mutation" because two nucleotides have been substituted in the mutated DNA sequence compared to the original DNA sequence.