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Fossil and genes are used to determine
A:how many mutations occurred in species of a time.
B:how many species interacted with each other.
C:differences between organisms.
D:how many species will change over time.

To determine the answer to this question, we need to understand the roles of fossils and genes in studying organisms. Let's break it down:

1. Fossils: Fossils are the preserved remains, impressions, or traces of organisms from the past. They provide valuable information about past life forms and their characteristics.

2. Genes: Genes are segments of DNA that carry the hereditary information of an organism. They determine the traits and characteristics of that organism.

Now let's evaluate each option and see which one aligns with the use of fossils and genes:

A: How many mutations occurred in species over time?
Fossils can give us an idea of the physical characteristics and biodiversity of past species, but they do not directly reveal the number of mutations that occurred. Genes, on the other hand, can be studied to identify mutations, but they alone cannot determine the number of mutations that occurred in a species over time. Therefore, option A is not correct.

B: How many species interacted with each other?
Fossils can provide evidence of species that coexisted or interacted in the past. However, fossils alone cannot provide a comprehensive view of species interactions. Genes do not directly tell us about species interactions either. Therefore, option B is also not correct.

C: Differences between organisms.
Both fossils and genes play significant roles in studying the differences between organisms. Fossils can show physical differences in structures, while genes can reveal genetic variations and differences among organisms. Therefore, option C is correct.

D: How many species will change over time?
While fossils and genes both provide information about how species have changed over time, they do not directly determine the number of species that will change. Predicting the number of species changes requires additional factors and analysis. Therefore, option D is not correct.

Based on our analysis, the correct answer is option C: differences between organisms. Fossils and genes are used to determine variations and dissimilarities among different organisms.