With respect to treating an acute myocardial infarction:
Identify a drug or treatment which has the effects listed
1)Activates plasminogen to lyse the thrombus.
a)Aspirin b)Warfarin c)Nitrate d)Morphine e)Tenectaplase f)oxygen
2)Helps to keep ischaemic cells alive
a)Aspirin b)Warfarin c)Nitrate d)Morphine e)Tenectaplase f)oxygen
3)Substrate for production of nitric oxide, a vasodilator.
a)Aspirin b)Warfarin c)Nitrate d)Morphine e)Tenectaplase f)oxygen
which one is correct help plz
In order to identify the correct drug or treatment for each effect listed, we need to understand their mechanisms of action. Let's break down each effect and analyze the options provided:
1) Activates plasminogen to lyse the thrombus:
- Aspirin: Aspirin is an antiplatelet agent that helps prevent blood clot formation, but it does not directly activate plasminogen.
- Warfarin: Warfarin is an anticoagulant and also does not directly activate plasminogen.
- Nitrate: Nitrates primarily work by dilating blood vessels to improve blood flow but do not activate plasminogen.
- Morphine: Morphine is an opioid analgesic and does not activate plasminogen.
- Tenectaplase: Tenectaplase is a thrombolytic drug that directly activates plasminogen to dissolve blood clots. Therefore, Tenectaplase is the correct option for this effect.
- Oxygen: While oxygen is important in the treatment of myocardial infarction, it does not directly activate plasminogen.
Correct answer: e) Tenectaplase
2) Helps to keep ischemic cells alive:
- Aspirin: Aspirin helps by preventing further clot formation but does not have a direct effect on ischemic cells.
- Warfarin: Warfarin does not have a direct effect on ischemic cells.
- Nitrate: Nitrates primarily help to dilate blood vessels and improve blood flow to ischemic areas, improving oxygen supply to tissues.
- Morphine: Morphine can have indirect effects by reducing pain and anxiety, which may help reduce cardiac workload, but it does not directly influence the survival of ischemic cells.
- Tenectaplase: Tenectaplase is a thrombolytic drug that helps dissolve blood clots and restore blood flow to ischemic areas, thereby aiding in the survival of ischemic cells.
- Oxygen: Administering supplemental oxygen can also help improve oxygen supply to ischemic tissues, assisting in the survival of ischemic cells.
Based on the options provided, both nitrates (c) and Tenectaplase (e) potentially help keep ischemic cells alive. However, since the question asks for a single option, either c) Nitrate or e) Tenectaplase can be considered correct.
3) Substrate for production of nitric oxide, a vasodilator:
- Aspirin: Aspirin does not directly serve as a substrate for the production of nitric oxide.
- Warfarin: Warfarin does not have a direct effect on nitric oxide production.
- Nitrate: Nitrates are converted to nitric oxide within the body, leading to vasodilation.
- Morphine: Morphine does not have a direct effect on nitric oxide production.
- Tenectaplase: Tenectaplase does not directly affect nitric oxide production.
- Oxygen: Oxygen does not directly affect nitric oxide production.
Based on the options provided, c) Nitrate is the correct option for being a substrate for the production of nitric oxide.
Correct answer: c) Nitrate
Please note that the information provided here is for educational purposes only. The selection of specific treatments should be based on the advice and guidance of healthcare professionals.