An individual with the genetic condition cystic fibrosis has CFTR protein with the amino acid histidine (at position 482), where the normal CFTR protein has arginine. (No other changes are observed in the protein.) This is the result of a _________ mutation.

Select one:
a. Nonsense.
b. Silent.
c. Frameshift.
d. Missense.

d. Missense. But don't worry, this is just a fancy way of saying that there has been a switcharoo in the amino acids! It's like playing a game of "guess the protein flavor" and someone slipped in histidine instead of the usual arginine. Sneaky little proteins!

d. Missense.

To determine the type of mutation, let's analyze the given information. We are told that an individual with cystic fibrosis has a specific amino acid substitution in the CFTR protein. Specifically, at position 482, histidine is present instead of the normal arginine.

Based on this information, we can determine that the mutation is a missense mutation. A missense mutation occurs when a single nucleotide change in the DNA sequence leads to the substitution of one amino acid with another in the resulting protein. In this case, the substitution of arginine with histidine at position 482 is a missense mutation because it results in a different amino acid being incorporated into the CFTR protein.