(d) Is this pedigree consistent with sex-linked dominant inheritance?
Yes
No
If you chose "yes", answer questions (i) and (ii) and leave parts (iii) and (iv) blank. If you chose "no", leave parts (i) and (ii) blank and answer questions (iii) and (iv).
i) If you chose "yes" above. Drag and drop in the appropriate genotype from the options below to indicate the genotypes of all the individuals in the pedigree. You may use each of the labels below once, more than once, or not at all. Note that the upper case letter indicates the allele with the dominant phenotype.
Xᴬ XᴬXᴬ X_Xᴬ XᵃXᵃ XᵃXᴬ YXᵃ Y
unanswered
ii) If you chose "yes" above. If Individuals 5 and 6 have another daughter, what is the probability that the girl will be affected by the disease? Please give a number between 0.0 and 1.0. Use as many significant digits as you need.
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iii) If you chose "no" above. Which set or sets of individuals is inconsistent with sex-linked dominant inheritance? Choose all that apply from the list below:
Individuals 1, 2, 3, and 5
Individuals 3, 4, 7, and 8
Individuals 5, 6, 9, and 10
Individuals 10, 11, 12, and 13
iv) If you chose "no" above. Can you change one individual from unaffected to affected and make this pedigree consistent with sex-linked dominant inheritance? If so, give the number of that individual. If it is not possible, enter 0.
unanswered
No. Individuals 1, 2, 3, and 5. AND
Individuals 5, 6, 9, 10, and 11.....
...give the number of that individual = 5.
To determine if this pedigree is consistent with sex-linked dominant inheritance, we need to analyze the given information.
If you chose "yes" above, it means that you believe this pedigree is consistent with sex-linked dominant inheritance. In that case, we need to identify the genotypes of all individuals in the pedigree. Here are the options you can drag and drop to indicate the genotypes:
Xᴬ - Homozygous dominant genotype
XᴬXᴬ - Homozygous dominant female genotype
X_Xᴬ - Heterozygous female genotype
XᵃXᵃ - Homozygous recessive genotype
XᵃXᴬ - Heterozygous female genotype
YXᵃ - Hemizygous recessive male genotype
Y - Homozygous recessive male genotype
Please drag and drop the appropriate genotype labels for all individuals in the pedigree. Once you have done that, you can move on to answer question (ii).
If you chose "no" above, it means that you do not believe this pedigree is consistent with sex-linked dominant inheritance. In that case, you should skip answering question (i) and (ii), and move on to question (iii) and (iv).
For question (iii), you need to determine which set(s) of individuals is inconsistent with sex-linked dominant inheritance. Choose all that apply from the options provided:
Individuals 1, 2, 3, and 5
Individuals 3, 4, 7, and 8
Individuals 5, 6, 9, and 10
Individuals 10, 11, 12, and 13
Select the set(s) of individuals that you believe are inconsistent with sex-linked dominant inheritance.
If you selected any option(s) in question (iii), move on to question (iv). For question (iv), you need to determine if it is possible to change one individual from unaffected to affected and make the pedigree consistent with sex-linked dominant inheritance. If it is possible, provide the number of that individual. If it is not possible, enter 0.
Once you have answered the questions, please provide your responses for (i), (ii), (iii), and (iv) respectively.