(c) Is this pedigree consistent with sex-linked recessive inheritance?

Yes
No
If you chose "yes", answer questions (i) and (ii) and leave parts (iii) and (iv) blank. If you chose "no", leave parts (i) and (ii) blank and answer questions (iii) and (iv).

i) If you chose "yes" above. Drag and drop in the appropriate genotype from the options below to indicate the genotypes of all the individuals in the pedigree. You may use each of the labels below once, more than once, or not at all. Note that the upper case letter indicates the allele with the dominant phenotype.

Xᴬ XᴬXᴬ X_Xᴬ XᵃXᵃ XᵃXᴬ YXᵃ Y
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ii) If you chose "yes" above. If Individuals 5 and 6 have another son, what is the probability that the boy will be affected by the disease? Please give a number between 0.0 and 1.0. Use as many significant digits as you need.

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iii) If you chose "no" above. Which set or sets of individuals is inconsistent with sex-linked recessive inheritance? Choose all that apply from the list below:

Individuals 1, 2, 3, and 5
Individuals 3, 4, 7, and 8
Individuals 5, 6, 9, and 10
Individuals 10, 11, 12, and 13
iv) If you chose "no" above. Can you change one individual from unaffected to affected and make this pedigree consistent with sex-linked recessive inheritance? If so, give the number of that individual. If it is not possible, enter 0.

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Numbered individuals?

Yes

Yes. (1) XA Xa (2) Xa Y

(3) Xa Xa (4) XA Y (5) XA Xa (6) XA Y
(7) XA Xa (8) XA Xa (9) XA X_ (10) Xa Y
(11) Xa Y
ii) If you chose "yes" above. If Individuals 5 and 6 have another son, what is the probability that the boy will be affected by the disease? 0.5

(1) XA Xa (2) Xa Y

(3) Xa Xa (4) XA Y (5) XA Xa (6) XA Y
(7) XA Xa (8) XA Xa (9) XA X_ (10) Xa Y
(11) Xa Y

To determine if the pedigree is consistent with sex-linked recessive inheritance, we need to evaluate the genotype patterns in the pedigree.

c) If you chose "yes" above, you need to answer questions (i) and (ii) and leave parts (iii) and (iv) blank.

i) Based on the given genotypes of the individuals, you need to drag and drop the appropriate genotype labels onto the pedigree. Each label should be used once, more than once, or not at all. The options are: Xᴬ, XᴬXᴬ, X_Xᴬ, XᵃXᵃ, XᵃXᴬ, YXᵃ, and Y.

ii) If Individuals 5 and 6 have another son, you need to calculate the probability that the boy will be affected by the disease. Provide a number between 0.0 and 1.0 with as many significant digits as needed.

If you chose "no" above, leave parts (i) and (ii) blank and answer questions (iii) and (iv).

iii) If you chose "no" above, you need to identify which set or sets of individuals in the pedigree are inconsistent with sex-linked recessive inheritance. Choose all that apply from the given options.

iv) If you chose "no" above, you need to determine if it is possible to change one individual from unaffected to affected and make the pedigree consistent with sex-linked recessive inheritance. If it is possible, provide the number of that individual. If it is not possible, enter 0.