The lethal inhalation dose of Sarin for a 200lb person has been determined to be 0.0015 mg. Determine the LD50 of Sarin that researchers used to calculate this lethal inhalation dose.
1.4 x 10-4 mg/kg
0.16 x 10-4 mg/kg
1.8 x 10-5 mg/kg
0.16 x 10-4 mg/kg
To determine the LD50 of Sarin that researchers used to calculate the lethal inhalation dose, we need to use the given information and equation. LD50 (median lethal dose) is the dose required to cause death in 50% of the population being tested.
The lethal inhalation dose of Sarin for a 200lb person has been determined to be 0.0015 mg. To calculate the LD50, we need to convert the weight from pounds to kilograms.
1 lb = 0.453592 kg
So, for a 200 lb person:
200 lb * 0.453592 kg/lb = 90.7184 kg
Now, we can use the equation LD50 (mg/kg) = lethal inhalation dose (mg) / weight (kg) to calculate the LD50.
LD50 (mg/kg) = 0.0015 mg / 90.7184 kg
Calculating this, we get:
LD50 (mg/kg) ≈ 1.65 x 10^-5 mg/kg
Therefore, the LD50 of Sarin that researchers used to calculate this lethal inhalation dose is approximately 1.65 x 10^-5 mg/kg.