does this word make sense in the sentence?

flustered

The speaker went right on with his speech, in no way flusterd or disturbed by the jeers and catcalls of a few rowdy hecklers.

Very good!

THANKS!

Yes, the word "flustered" makes sense in the sentence. It is used to describe the speaker's state of being calm and composed, not affected by the jeers and catcalls of the hecklers.