Match the poison/drug to the effect.
a. curare b. tetanus toxin c. a-bungarotoxin d. strychnine e. botulinum toxin
f. neostigmine
__________ causes spastic paralysis by specifically blocking glycine receptors
__________ causes flaccid paralysis by blocking the release of acetylcholine
__________ causes spastic paralysis by blocking inhibitory synapses in the CNS
__________ a botanical that causes flaccid paralysis by blocking nicotinic Ach (acetylcholine) receptors on postsynaptic cells
__________ is used to improve muscle tone in the skeletal muscles; inhibits acetylcolinesterase and thus prolongs the presence of the neurotransmitter in the synaptic cleft
___________ derived from snake venom, it irreversibly binds to nicotinic receptors on skeletal muscle cells
a. curare - causes flaccid paralysis by blocking nicotinic Ach (acetylcholine) receptors on postsynaptic cells
b. tetanus toxin - causes spastic paralysis by blocking inhibitory synapses in the CNS
c. a-bungarotoxin - derived from snake venom, it irreversibly binds to nicotinic receptors on skeletal muscle cells
d. strychnine - causes spastic paralysis by specifically blocking glycine receptors
e. botulinum toxin - causes flaccid paralysis by blocking the release of acetylcholine
f. neostigmine - is used to improve muscle tone in the skeletal muscles; inhibits acetylcolinesterase and thus prolongs the presence of the neurotransmitter in the synaptic cleft
To match the poison/drug to the effect, we need to understand the actions of each substance. Here's a breakdown of each one:
a. curare: It causes flaccid paralysis by blocking the release of acetylcholine.
b. tetanus toxin: It causes spastic paralysis by specifically blocking glycine receptors.
c. a-bungarotoxin: It causes spastic paralysis by blocking inhibitory synapses in the CNS.
d. strychnine: It is a botanical poison that causes flaccid paralysis by blocking nicotinic acetylcholine receptors on postsynaptic cells.
e. botulinum toxin: It causes flaccid paralysis by blocking the release of acetylcholine.
f. neostigmine: It is used to improve muscle tone in skeletal muscles. It inhibits acetylcholinesterase, which prolongs the presence of the neurotransmitter acetylcholine in the synaptic cleft.
Now we can match the substances to their effects:
a. curare: Flaccid paralysis
b. tetanus toxin: Spastic paralysis
c. a-bungarotoxin: Spastic paralysis
d. strychnine: Flaccid paralysis
e. botulinum toxin: Flaccid paralysis
f. neostigmine: Improve muscle tone in skeletal muscles
Please note that the effects of these substances are simplified explanations, and in reality, their actions may be more complex.