Can anyone help ..

State the functional groups that the BZP and TFMPP in Party Pills and MDMA have in common.

ph //-\\/CF3
/ [[ ]]
[ N ] \\ // < Benzine
[
[ N ] / N \
\H/ [ ]
\ N /
(BZP) H (TFMPP)

/ \
0 0
\- /
//-\\ Benzene
\ - /
\_/Me
\NHMe MDMA Ectasy

Me is used as an abbreviation for the methyl; CH 3 group

I think they all have the amine NH functional group in common is that right ???

Have been asked to suggest why party pill may have similar pharmacological activity to to amphetamines ???

Thanks

Sorry about the layout !

It is hard to draw structures on here!

BZP is benzyl piperazine. It has a secondar amine, tertiary amine and a benzene ring (if you are counting this as a FG).

3-Trifluoromethylphenylpiperazine (TFMPP) has the same functional groups. The trifluoromethyl group is not normally considered to be a functional group.

MDMA (3,4-Methylenedioxymethamphetamine) or ecstacy has a secondary amine group, a benzene ring (if you count this) and methylenedioxy (which are ether functional groups).

So in common they have a secondary amine group and the benzene ring.

They all have similar structures to the basic amphetmine structure

http://en.wikipedia.org/wiki/Amphetamines

It is easier if you can make models of thse and compare them.

Thank you Dr Russ !

Yes, you are correct! BZP and TFMPP in party pills, as well as MDMA (ecstasy), all share a common functional group which is the amine NH group.

To identify the functional groups, you can look for distinct patterns or groups of atoms within the chemical structure. In this case, the amine NH group is present in all three compounds.

As for why party pills may have similar pharmacological activity to amphetamines, one possible reason is that both party pills and amphetamines stimulate the release of neurotransmitters such as dopamine, norepinephrine, and serotonin in the brain. This can lead to increased energy, euphoria, and heightened mood, which are commonly associated with both party pills and amphetamines.

Please note that the information provided here is for educational purposes only and should not be considered medical advice. It is always important to consult with a healthcare professional for accurate and personalized information regarding drugs and their effects.