with would be more convenient?

(A) burn 1 mole of carbon with 2 moles of sulfur and mesure the energy yield
(B) burn 602,000,000,000,000,000,000,000 atoms of carbon with 1,204,000,,000,000,000,000,000,000 atoms of sulfur and measure the energy yield.

Choice A and Choice B are the same thing.

To determine which option would be more convenient, we need to compare the practicality and ease of carrying out each option.

(A) Burning 1 mole of carbon with 2 moles of sulfur and measuring the energy yield:
This option involves using the moles of carbon and sulfur, which is a widely used unit of measurement in chemistry. If you have the necessary equipment to accurately measure and control moles of substances, this method can be relatively straightforward. However, accurately measuring moles requires precise weighing and may need specialized equipment, such as a balance, to carry out the experiment.

(B) Burning 602,000,000,000,000,000,000,000 atoms of carbon with 1,204,000,000,000,000,000,000,000 atoms of sulfur and measuring the energy yield:
This option involves counting the number of atoms instead of using moles. Counting such an enormous number of atoms manually is impractical and time-consuming. It would be extremely challenging, if not impossible, to accurately count this many atoms. Therefore, this method is not convenient or feasible.

Given these considerations, option (A) would be more convenient because it relies on a standard unit of measurement (moles) and can be realistically achieved with the appropriate equipment.