Which of the following statements is TRUE regarding bile?


Bile is produced by the gall bladder, and secreted into the duodenum

Bile is produced and secreted in response to CCK, which is in turn secreted primarily in response to high acidity of duodenal chyme

Bile is most important in the digestion of proteins

Bile injection into the duodenum is caused by the relaxation of the sphincter of Oddi and the contraction of the gall bladder

Bile injection into the duodenum is caused by the relaxation of the sphincter of Oddi and the contraction of the gall bladder

To determine which of the statements is true regarding bile, let's analyze each option:

Statement 1: Bile is produced by the gall bladder and secreted into the duodenum.
This statement is incorrect. Bile is produced by the liver, not the gall bladder. However, the gall bladder does store and concentrate bile produced by the liver before releasing it into the duodenum when needed.

Statement 2: Bile is produced and secreted in response to CCK, which is in turn secreted primarily in response to high acidity of duodenal chyme.
This statement is mostly true. Bile secretion is regulated by the hormone cholecystokinin (CCK), which is released in response to the presence of fatty acids and amino acids in the duodenum. However, CCK is not primarily secreted in response to high acidity but instead in response to the presence of fats and proteins in the duodenum.

Statement 3: Bile is most important in the digestion of proteins.
This statement is incorrect. Although bile does play a role in digestion, its primary function is the emulsification and absorption of fats, not proteins. Bile helps break down fats into smaller droplets, increasing their surface area for enzymes to act upon.

Statement 4: Bile injection into the duodenum is caused by the relaxation of the sphincter of Oddi and the contraction of the gall bladder.
This statement is true. The release of bile into the duodenum is indeed caused by the relaxation of the sphincter of Oddi, which allows bile to flow from the common bile duct into the duodenum. Simultaneously, the contraction of the gall bladder helps push the stored bile into the common bile duct.

In conclusion, the true statement regarding bile is:
Bile injection into the duodenum is caused by the relaxation of the sphincter of Oddi and the contraction of the gall bladder.

The true statement regarding bile is:

Bile is produced by the gall bladder, and secreted into the duodenum.