Are the following sentences punctuated correctly?

The patient’s mother, despite multiple attempts, was unable to be reached.

His unusual contradictory explanation requires a psychiatric workup.

Before we begin surgery he needs to be seen by the anesthesia service.

Sentence one is awkward, but correctly punctuated.

Sentences two and three are incorrect.
http://grammar.ccc.commnet.edu/grammar/commas.htm
See #s 3 and 5.

Yes, the sentences are punctuated correctly.

1. "The patient’s mother, despite multiple attempts, was unable to be reached."

Explanation:

- The sentence begins with an introductory phrase, "The patient's mother," which is followed by a comma.
- The main clause follows, "was unable to be reached," without any need for additional punctuation.
- The phrase "despite multiple attempts" is enclosed by commas because it provides extra information about the patient's mother.
- There is a period at the end of the sentence to indicate the end of the sentence.

2. "His unusual contradictory explanation requires a psychiatric workup."

Explanation:

- The sentence begins with "His unusual contradictory explanation," followed by a comma.
- The main clause follows, "requires a psychiatric workup," without any need for additional punctuation.
- There is a period at the end of the sentence to indicate the end of the sentence.

3. "Before we begin surgery he needs to be seen by the anesthesia service."

Explanation:

- The sentence begins with an introductory phrase, "Before we begin surgery," which is followed by a comma.
- The main clause follows, "he needs to be seen by the anesthesia service," without any need for additional punctuation.
- There is a period at the end of the sentence to indicate the end of the sentence.