What is the difference between Miss and Ms.?

The difference between Ms. and Miss is that Ms. can stand for Mrs. or Miss, so in essence, the woman who goes by Ms. is not giving away whether she is married or not married. Miss strictly refers to a woman who is not married. Mrs. is the term you would use for a married woman. If you were addressing a woman that you didn’t know, the safest term would be Ms. because you don’t know if she is married or not.