What evidence exists to support the theory of evolution at the amino acid level

https://www.ncbi.nlm.nih.gov/books/NBK230201/

https://www.sparknotes.com/biology/evolution/evidence/section4/

The theory of evolution is supported by extensive evidence from multiple scientific disciplines, including genetics, paleontology, comparative anatomy, and biochemistry. At the amino acid level, there are several lines of evidence that support the theory.

1. Homology: Homologous amino acid sequences found across different species provide evidence for a common ancestry. Homology refers to similarities in the genetic code or protein sequences that indicate a shared evolutionary history. For example, many proteins involved in basic cellular processes, such as enzymes or structural proteins, have similar amino acid sequences among diverse species. This similarity suggests that these proteins have been inherited from a common ancestor.

2. Genetic Variation: Genetic variation within populations and species is another strong piece of evidence for evolution. At the amino acid level, mutations or changes in the DNA sequence can result in different amino acids being incorporated into proteins. This variation can lead to functional differences or changes in protein structure, potentially providing an advantage or disadvantage to an organism in a particular environment. Over time, these genetic variations, when beneficial, can accumulate and lead to the development of new traits, promoting evolutionary change.

3. Molecular Clocks: Molecular clocks are based on the observation that the rate of genetic mutation is relatively constant over time. By comparing the differences in amino acid sequences between related species, scientists can estimate the divergence time between them. This method has been used to construct evolutionary timelines and phylogenetic trees, showing the relationships between different species and when they diverged from a common ancestor.

4. Convergent Evolution: Convergent evolution occurs when unrelated species independently evolve similar traits due to similar environmental pressures. At the amino acid level, this convergence can be observed in the similarities of protein structures or functions in distantly related species. For example, enzymes with similar functions but different amino acid sequences can be found in organisms as diverse as bacteria and humans. Convergent evolution provides evidence that similar solutions to environmental challenges can arise independently, supporting the idea of natural selection.

To explore these pieces of evidence further, you can study scientific literature, evolutionary biology textbooks, or research papers that delve into specific examples and experiments. Additionally, you can engage with professional scientific organizations or consult with experts in the field for a comprehensive understanding of the evidence supporting evolution at the amino acid level.