How many molecules of ATP are produced from the β oxidation of linoleate? (please answer the ?s)
Linoleate is a (?) carbon fatty acid. If it were completely saturated,
(?) ATP would be generated via β oxidation. However, linoleate has one double bond at the 9,10 position, which must be converted from the cis to the trans isomer, resulting in the loss of (?) QH2 ( (?)ATP). In addition, an NADPH-dependent reduction of the 12,13 double bond costs (?) ATP. This reduces the ATP total by (?), so oxidation of linoleate yields (?)ATP.
To determine the number of molecules of ATP produced from the β oxidation of linoleate, we need to break down the information provided.
1. Linoleate is a 18-carbon fatty acid.
2. If linoleate were completely saturated, it would theoretically generate 9 ATP molecules from β oxidation.
3. Since linoleate has one double bond at the 9,10 position, it needs to be converted from the cis to the trans isomer.
4. This conversion results in the loss of 1 molecule of QH2 (a form of reduced coenzyme Q) which corresponds to 1 ATP molecule.
5. Additionally, there is an NADPH-dependent reduction of the 12,13 double bond, which costs 1 ATP molecule.
6. These losses reduce the ATP total by 2, so the oxidation of linoleate yields 7 ATP molecules.
Therefore, the number of molecules of ATP produced from the β oxidation of linoleate is 7.
Linoleate is an 18 carbon fatty acid.
If it were completely saturated, 129 ATP would be generated via β oxidation.
However, linoleate has one double bond at the 9,10 position, which must be converted from the cis to the trans isomer, resulting in the loss of 1 QH2 (2 ATP).
In addition, an NADPH-dependent reduction of the 12,13 double bond costs 1 ATP.
This reduces the ATP total by 3, so oxidation of linoleate yields 126 ATP.