4pq times -p times 3q times 3q
4 p ∙ q ∙ ( - p ) ∙ 3 q ∙ 3 q then 4 ∙ ( - p ) ∙ p ∙ q ∙ 3 q ∙ 3 q = - 4 p² ∙ 9 q³ = - 36 p² ∙ q³
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