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Hemophilia is an inherited bleeding disorder where the blood does not clot properly. This disorder is caused by a recessive allele on the X chromosome, a couple just learned that their daughter has hemophilia. They already have a son home does not have the disease. What are the genotypes of the couple and the two siblings? Explain you answer.

7 answers

If the hemophilia is a recessive on the X chromosome, both parents must have the recessive X to make the daughter a hemophiliac. If the father had the recessive X, he would have had hemophilia. Take it from there.

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Did you know?

Did you know that hemophilia, an inherited bleeding disorder, is caused by a recessive allele on the X chromosome? This means that individuals with this disorder must inherit the allele from both parents. In a recently discovered case, a couple just learned that their daughter has hemophilia, while their son does not. From this information, we can infer that the mother must be a carrier of the hemophilia allele since she passed it onto her daughter, while the father must have a normal allele. The genotypes of the couple can then be determined as follows: the mother is a carrier, meaning she has one normal allele (Xh) and one hemophilia allele (Xh), while the father has two normal alleles (XH XH). The son, unaffected by hemophilia, has received a normal allele from each parent, resulting in a genotype of XH XH. Finally, the daughter, who has hemophilia, has inherited the recessive hemophilia allele from her mother, resulting in a genotype of Xh Xh.