what is the importance of ph to biological systems in the human body?

I have an answer but is there anything else I could include and is my answer justified?

My answer:
Changes in the ph could be harmful, Natural buffers prevent rapid or large changes in the pH of living things. For example, humans have ways of balancing their pH in blood with bicarbonate. Our kidneys alter the amounts of excess bases and acids as well.

Is there anything else I could included?

Ok thanks :)

Your answer is a good start, but there are a few additional points you could include to enhance it:

1. pH homeostasis: One of the main reasons pH is important in biological systems is because many biochemical reactions in the human body are highly sensitive to pH levels. Different enzymes and proteins function optimally within specific pH ranges. Any deviation from these optimal ranges can disrupt their functionality and potentially lead to health issues. Maintaining a stable pH, also known as pH homeostasis, is crucial for proper physiological functioning.

2. Acid-base balance: The human body has several mechanisms to regulate pH and maintain a constant acid-base balance. For instance, bicarbonate ions act as important buffer systems in the blood, maintaining its pH within a narrow range (around 7.35-7.45). This buffering system involves the conversion between carbon dioxide and bicarbonate ions, enabling the blood to resist pH changes caused by acid or base inputs.

3. Respiratory and renal regulation: In addition to buffering systems, the human body utilizes respiratory and renal mechanisms to regulate pH. Our lungs help control pH by controlling the elimination of carbon dioxide, which is acidic when dissolved in water. Through the release or retention of carbon dioxide, breathing rate can be adjusted to maintain pH balance. The kidneys also play a vital role by excreting excess acids or bases in the urine, thus influencing systemic pH regulation.

4. Cellular processes: pH impacts various cellular processes in the body. For example, proper functioning of ion channels and pumps is dependent on specific pH conditions. pH levels can also affect the solubility and structure of molecules, including proteins and nucleic acids, impacting their functionality. Thus, maintaining appropriate pH levels is critical for cellular metabolism and overall health.

By including these additional points, your answer would be more comprehensive and justified.