51. A fragment of mRNA with the sequence 5' ACGCAUGGCAAAAAAAA 3' will have a template DNA sequence that reads
A. 3' UGCGUACCGUUUUUUUU 5'.
B. 3' TTTTTTTTGCCATGCGT 5'.
C. 3' UUUUUUUUGCCATGCGT 5'.
D. 3' TGCGTACCGTTTTTTTT 5'
D. 3' TGCGTACCGTTTTTTTT 5'
To find the template DNA sequence, we need to remember the base-pairing rules for DNA and RNA. In DNA, adenine (A) pairs with thymine (T) and guanine (G) pairs with cytosine (C). In RNA, uracil (U) replaces thymine (T).
In the mRNA sequence 5' ACGCAUGGCAAAAAAAA 3', we can determine the template DNA sequence by replacing each RNA base with its complementary DNA base:
- A (adenine) pairs with T (thymine)
- C (cytosine) pairs with G (guanine)
- G (guanine) pairs with C (cytosine)
- U (uracil) pairs with A (adenine)
Therefore, the template DNA sequence will be 3' TTTTTTTTGCCATGCGT 5'.
Option B. 3' TTTTTTTTGCCATGCGT 5' is the correct answer.
To determine the template DNA sequence that corresponds to the given mRNA sequence, you need to understand the pairing rules between RNA and DNA bases.
In RNA, adenine (A) pairs with uracil (U), and guanine (G) pairs with cytosine (C). In DNA, adenine (A) pairs with thymine (T), and guanine (G) pairs with cytosine (C).
To find the template DNA sequence, we need to substitute the RNA base U with its complementary DNA base T, and the remaining RNA bases (A, C, and G) with their complementary DNA bases (T, G, and C).
The given mRNA sequence is: 5' ACGCAUGGCAAAAAAAA 3'
So, the template DNA sequence would be: 3' TGCATACCGTTTTTTTT 5'
Therefore, the correct answer is option D: 3' TGCGTACCGTTTTTTTT 5'.