Compute dy/dx using the chain rule.

y = (u/4) + (4/u)

u = (x - x^7)

dy/dx =

well, just plug and chug

dy/dx = dy/du * du/dx
= (1/4 - 4/u^2)(1 - 7x^6)
= 1/4 (1-16/(x-x^7)^2)(1-7x^6)

and you can massage that as you like