Amide + Acetone -> ammonia + Acetone Enolate
Weaker acid:
Conjugate Base:
Species that predominate at equilibrium(2):
Please Help!
To determine the weaker acid, conjugate base, and species that predominate at equilibrium in the given reaction, we need to compare the acidities of the reactants.
In the reaction:
Amide + Acetone -> Ammonia + Acetone Enolate
Amide acts as a weak base and Acetone acts as a weaker acid.
To determine the weaker acid, we compare the acidity of Acetone with Ammonia, which is the conjugate acid of the Amide. In general, comparing the acidity of an organic compound involves looking at the stability of the conjugate base.
Ammonia is a weaker acid compared to Acetone because its conjugate base, Amide, is more stable than the conjugate base of Acetone. Amide has a negative charge on the nitrogen atom, which is stabilized by resonance delocalization. Whereas, the conjugate base of Acetone, which is Acetone Enolate, has a negative charge on an oxygen atom, which is less stabilized by resonance.
Therefore, Acetone is the weaker acid compared to Ammonia.
For the weaker acid (Acetone), the conjugate base is Acetone Enolate.
Species that predominate at equilibrium (2):
Since Acetone is a weaker acid compared to Ammonia, the equilibrium position of the reaction will favor the formation of Acetone Enolate. Therefore, Acetone Enolate will predominate at equilibrium.
The second species that predominates at equilibrium will be determined by the reaction conditions, such as the concentration of the reactants and any possible catalysts. Without further information, it is difficult to determine the exact second species that will predominate at equilibrium.