You want to study the effects on the organism of high circulating levels of LDL using a mouse model. Which one of the following tools would be best to use in your studies?
add an extra copy of the HMG CoA reductase gene fused to the GFP coding
sequence
add an extra copy of the LDL receptor gene fused to the GFP coding sequence
create a mouse where the gene encoding the HMG CoA reductase has been knocked out create a mouse where the gene encoding the LDL receptor has been knocked out
add an extra copy of the gene encoding LDL receptor