Which of these two sentences is correct? Is there a different correct format?

This construction is different than in English.
This construction is different from English.

Neither is completely correct. Here's how I'd rephrase:

This construction in Spanish is different from that in English. (Change the languages to whatever you want.)

http://www.google.com/search?q=different+from+different+than+grammar&oq=%22different+from%22+%22different+than%22&aqs=chrome.3.69i57j0l5.15669j0j7&sourceid=chrome&es_sm=119&ie=UTF-8