Holly knows from talking with Renee that genes control traits and are determined by the sequence of nucleotides. When that sequence of nucleotides is altered for some reason during DNA replication, it can lead to the gene being expressed in a different way or to a genetic disorder.

During DNA replication, mistakes are sometimes made. For example, a mistake might include when a base is removed from the sequence. This specific change is called a(n) (A) __________). These types of mistakes are called (C) __________.

(A) The specific change when a base is removed from the sequence during DNA replication is called a deletion.

(C) These types of mistakes, including deletions, are called mutations.

To answer the question, we need to fill in the blanks.

A) The specific change when a base is removed from the sequence during DNA replication is called a deletion.

C) These types of mistakes, including base deletions, are called mutations.

To get the answer, we can look for information about DNA replication and the types of mistakes that can occur. DNA replication is a biological process where a copy of DNA is created. Mistakes or errors can occur during this process, leading to genetic mutations. Specific changes such as base deletions can alter the sequence of nucleotides, which can impact gene expression or lead to genetic disorders.