Microorganisms develop resistance to antimicrobial drugs in a number of ways, EXCEPT
A. Producing an enzyme that deactivates the antimicrobial drug
B. Changing the cellular permeability to prevent the drug from entering the cell
C. Interfering with the cell wall synthesis of the microorganism
D. Altering binding sites on the membranes or ribosomes, no longer accepting the drug
Is it D?
No, it is not option D. Microorganisms can develop resistance to antimicrobial drugs by altering binding sites on the membranes or ribosomes, no longer accepting the drug. The correct answer is likely C. Interfering with the cell wall synthesis of the microorganism.
To determine the correct answer, let's analyze each option:
A. Producing an enzyme that deactivates the antimicrobial drug: Some microorganisms can produce enzymes that inactivate specific antimicrobial drugs by breaking them down. This is a mechanism through which microorganisms can develop resistance.
B. Changing the cellular permeability to prevent the drug from entering the cell: Microorganisms can modify their cellular membranes to reduce the entry of antimicrobial drugs, which helps them develop resistance.
C. Interfering with the cell wall synthesis of the microorganism: Some antimicrobial drugs target the cell wall synthesis of microorganisms, disrupting their ability to build a strong cell wall. Microorganisms may develop resistance by altering their cell wall synthesis process.
D. Altering binding sites on the membranes or ribosomes, no longer accepting the drug: This option suggests that microorganisms can alter the binding sites on their membranes or ribosomes, which prevents the antimicrobial drug from attaching and inhibiting their function.
Based on the explanations, it seems that all the options provided represent potential mechanisms of resistance that microorganisms may utilize to develop resistance to antimicrobial drugs. Therefore, none of the options can be excluded as an incorrect answer.
So, the answer is not D, because all the options are valid potential ways in which microorganisms can develop resistance to antimicrobial drugs.