Describe the steps (and the glassware used) to making 100 mL of a 1 M Tris pH 7.8.

Let's see.

M = mols/L; therefore,
# mols = M x L
You have M = 0.100 and you have L - 0.100 so you want 0.01 mols of the base and 0.01 mols of the salt (the acid) (since the problem states you want an equimolar solution of base and acid.
After you know mols, then mols = grams/molar mass. You know molar mass and you know the mols, calculate grams of the base and grams of the salt (acid). Voila!......"by.DRbob222"

But does the problem say equimolar. The pKa I looked up is 8.1 and you want pH of 7.8 so that isn't equimolar. Close but not quite.

To make 100 mL of a 1 M Tris solution with pH 7.8, you will need the following steps and glassware:

1. Determine the amount of Tris base needed: The molarity of the solution can help calculate the amount of Tris base required. Since Tris is a weak base, you will need to take the pKa into account. In this case, Tris has a pKa of around 8.1, so to achieve pH 7.8, you will need to use the base form of Tris. Calculations show that you will need approximately 30.33 g of Tris base (121.14 g/mol) for a 1 M solution.

2. Choose an appropriate glassware: You will need a glassware container that can hold at least 100 mL volume and has accurate gradations for measurements. A graduated cylinder or a volumetric flask would be suitable choices.

3. Weigh the Tris base: Use a weighing balance (electronic or analytical balance) to measure out 30.33 g of Tris base accurately. Place a clean weighing boat or beaker on the balance, tare it to zero (if using a digital balance), and then transfer the exact amount of Tris base.

4. Add distilled water: Take the chosen glassware and add approximately half of the required final volume of distilled water, which is 50 mL. You can use a clean and calibrated pipette or a graduated cylinder for measuring the distilled water.

5. Dissolve the Tris base: Slowly add the weighed Tris base into the glassware containing the distilled water while stirring. Use a glass rod or a magnetic stir bar to mix the solution thoroughly until the Tris base completely dissolves.

6. Adjust the pH: To achieve pH 7.8, you will need to use a pH meter or pH indicator. Start by adding a small amount of concentrated hydrochloric acid (HCl), dropwise, while monitoring the pH. Continue adding until the pH reaches 7.8. It is advisable to use a pH meter for accurate pH adjustments.

7. Complete the final volume: Once the desired pH is achieved, add more distilled water to make up the final volume of 100 mL. You can use the same glassware for this step, ensuring the volume markings on the glassware are accurate.

8. Mix the solution: After adjusting the final volume, mix the solution gently by swirling or inverting the glassware a few times to ensure homogeneity.

Remember to handle chemicals and glassware with proper safety precautions, including using gloves, goggles, and a lab coat. Also, consult reliable references or experts for specific guidelines or variations in the procedure depending on your specific requirements.