1. Why don't you take a few days off?

2. Why don't you take off a few days?
--------------------------
Are both the same in meaning? What other expressions can we use instead of 'take off'?

They are the same in meaning, but 1 is, by far, the smoother phrasing.

Why don't you take a few days for yourself?
Why don't you take a break for a few days?