is the cis-regulatory sequence found in the exome?

To determine if the cis-regulatory sequence is found in the exome, we need to understand what each term refers to.

The exome refers to the portion of the genome that contains the protein-coding genes. It comprises approximately 1-2% of the entire genome. On the other hand, cis-regulatory sequences are non-coding DNA regions that regulate the expression of nearby genes. They control when and where a gene is turned on or off.

Given that cis-regulatory sequences are non-coding regions, they are not part of the exome, which only includes the protein-coding genes. Cis-regulatory sequences are typically found in the upstream or downstream regions of genes, and can be located within introns or intergenic regions.

To determine the presence of cis-regulatory sequences, researchers need to use various computational and experimental techniques, such as comparative genomics, DNA footprinting, and functional reporter assays, to identify these regulatory regions. They often focus on specific regions of interest and analyze whether they contain the binding sites for transcription factors or other elements involved in gene regulation.