1. Differentiate drug tolerance from physical dependence.

A: Drug tolerance is a condition in which a user need more of a drug to feel the same effect felt when first using the drug, whereas physical dependence is a states in which the body relies upon a given drug in order to function.

Right.

To differentiate drug tolerance from physical dependence, you need to understand the key distinctions between these two terms.

1. Drug Tolerance:
- Drug tolerance refers to the body's diminishing response to a drug with repeated use.
- It occurs when the same amount of a drug produces a reduced effect or requires a higher dose to achieve the desired effect.
- Drug tolerance is specific to the drug being used and can occur both with addictive and non-addictive substances.
- It is a physiological adaptation that primarily affects the brain's receptors and neurotransmitter systems.

2. Physical Dependence:
- Physical dependence is a state in which the body adapts to the presence of a drug and develops withdrawal symptoms if the drug is suddenly stopped or significantly reduced.
- It is a consequence of prolonged drug use, leading to chemical changes in the brain and a reliance on the drug to function normally.
- Physical dependence can occur with certain drugs, including opioids, sedatives, and stimulants.
- Withdrawal symptoms can be physical, such as nausea, tremors, or sweating, or psychological, such as anxiety or depression.

In summary, drug tolerance refers to the body's reduced response to a drug with repeated use, while physical dependence is a state of reliance on a drug to avoid withdrawal symptoms. Drug tolerance is related to the effects of the drug, whereas physical dependence is centered around the body's need for the drug to function normally.