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Base line BP:120,145, 130,160,152,143,126.
After 4 week:122,142,135,158,155,140,130.
A clinical trial is planned to compare an experimental medication to lower blood pressure. a pilot study is conducted involving 7 subjects.The objective was to see how BP changes over time without medication.Is there any statistical significant difference in BP over time. Run test at a 5%level of significance.

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