What African American was the first to star in a major television show in 1965 called "I Spy"?

Bill Cosby?

Right.

Yes, you are correct. Bill Cosby was the first African American to star in a major television show in 1965 called "I Spy." To find the answer to this question, you can use a search engine such as Google or Bing. Simply type in the question "Who was the first African American to star in a major television show in 1965 called 'I Spy'?" and the search engine will provide you with the answer, which is Bill Cosby.