posted by erica .
How did human history in North America during the period described in the Prologue differ from the events of Asia, Eurasia, and Europe? Be specific.
How were these differences important to the international state of affairs in 1450?
this is using the american nation: a history of the united states 13th edition
We have no idea what's described in the prologue.
However, in 1450, Asia and Europe had no knowledge of the Americas. Therefore, the culture of the Americas played no part in the affairs of the rest of the world.