(sqr root of 2 + 3*sqr root of 5)(sqr root of 2-3*sqr root of 5)

(√2 + 3√5)(√2 - 3√5)

this has the pattern for the difference of squares
(a + b)(a - b) = a^2 - b^2

so your question has an answer of
(√2)^2 - (3√5)^2
= 2 - 45
= -43