1. Look at her facial expression.

2. Look at her appearance.
3. Look at her looks.

4. How does she look?
- She looks satisfied?

5. How do you think she looks?
- I think she looks unsatisfied.

(Can we use all the expressions? Do we have to use a singular expression or a plural expression in #2 and #3 ?)

Plural in 3, but singular everywhere else.

1. facial expression = the look on her face

2 and 3. appearance, looks = could be just her facial expression, but more likely this is referring to all of her, such as these:
Her appearance is very stylish.
Her looks are quite ordinary.
She looks disheveled.
http://www.answers.com/topic/disheveled

In expressions 2 and 3, "appearance" and "looks" can refer to both singular and plural entities. So, you can use either singular or plural subjects in these expressions.

Now, let's address the questions you asked:

1. "Look at her facial expression." - To answer this, observe the person's face and pay attention to their facial muscles, eye movements, and overall demeanor to gauge their emotional state or reaction.

2. "Look at her appearance." - To answer this, observe the person's physical characteristics such as their clothing, grooming, body language, and general demeanor to form an impression about their overall presentation.

3. "Look at her looks." - This expression is similar to the previous one, where you assess the person's physical appearance as a whole, taking into account their clothing, grooming, body language, and general demeanor to form an impression about how they look or present themselves.

4. "How does she look?" - To answer this question, you would describe the person's appearance based on your observations. For example, if she looks satisfied, you would respond with "She looks satisfied."

5. "How do you think she looks?" - In this case, you are expressing your opinion or conjecture about her appearance. If you think she looks unsatisfied, that would be your answer: "I think she looks unsatisfied."

Remember to always be respectful when describing someone's appearance and rely on your observations to provide an accurate response.