RFLP analysis of some blood from a crime scene shows that the blood belongs to someone with genotype D1/D3, E2/E5, F5/F5, G1/G3. the frequencies of these genotypes in the Caucasian population are D1/D3 =0.01, E2/E5= 0.02, F5/F5= 0.001, G1/G3= 0.00001. What proportion of the Caucasian population shares this genotype with this person.
a. 0.0311
b. 0.0001
c. 0.00005
d. 0.000001
e. 2 * 10^-11
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Multiply the probabilities of each of the 4 matches. That gives 2*10^-12. Did you type one too many zeros somewhere?
To determine the proportion of the Caucasian population that shares the genotype with this person, you need to calculate the product of the frequencies of each individual genotype.
For genotype D1/D3, the frequency is 0.01.
For genotype E2/E5, the frequency is 0.02.
For genotype F5/F5, the frequency is 0.001.
For genotype G1/G3, the frequency is 0.00001.
To calculate the proportion, multiply these frequencies together:
Proportion = 0.01 * 0.02 * 0.001 * 0.00001
= 0.0000000002
This can also be written as 2 * 10^-10, which matches with option e. Therefore, the correct answer is e. 2 * 10^-11.