Compound B is acetylcholine, a neurotransmitter found in the human body. It binds to receptors, leading to nerve stimulation. (in case this post does not show correct, two of the CH3 should be above and below the N^+ , AND THE O should be above the C)
COMPOUND B
CH3 O
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H3C- N+- CH2- CH2- O-C- CH3
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CH3
(i)
Name two types of interaction, other than van der Waals or hydrophobic interactions, by which compound B could bind to the receptors.
(ii)
Identify two different types of group or atoms that could be involved in each of the interactions described in part (c)(i).
(iii) Give examples of the types of functional groups which will have to be present in the receptor sites in order for the two types of binding interaction to take place.
This is an OU S104 assignment question, TMA04 Q5c, and posting it is considered to be cheating. Your post will be forwarded to the course team.
To answer these questions, we need to consider other types of interactions that allow compound B (acetylcholine) to bind to receptors. Here's how we can go about finding the answers:
(i) Search for alternative binding interactions:
To find two types of interactions, other than van der Waals or hydrophobic interactions, by which compound B could bind to receptors, we can search for known interactions involved in molecular binding. Some common interactions to consider are hydrogen bonding, electrostatic interactions, and covalent bonding.
(ii) Identify groups or atoms involved in each interaction:
Once we have identified the alternative interactions, we need to identify the specific groups or atoms involved in each interaction. For example, in hydrogen bonding, groups like -OH, -NH, or -COOH may be involved. In electrostatic interactions, charged groups like amino acids with positive or negative charges may play a role. For covalent bonding, reactive functional groups such as -SH or -OH may be important.
(iii) Identify functional groups in receptor sites:
To determine examples of functional groups present in the receptor sites, we need to consider the requirements for each specific interaction. For example, if hydrogen bonding is one of the interactions, the receptor site should have groups capable of forming hydrogen bonds, such as -OH or -NH2. If electrostatic interactions are involved, charged functional groups like amino acids with charges might be required.
To answer the questions fully, it would require further research into the specific interactions involved in the binding of acetylcholine to receptors and the corresponding functional groups within receptor sites.