IS IT RIGHT TO MAKE CHANGES TO THE QUALITIIES OF HUMANS!

In what way? We change all the time. Parents try to impress cultural norms and qualities. School teachers engage students with qualities of learning. Doctors change the quality of individual's lives through medical interventions and that of groups through inocculations.

(PS please don't shout = use capitals)

Behavioral changes have been made in children as long as parenting existed. Behavioral changes are made in adults as long as jobs and supervisors have existed. I have a daughter who is 29 years old, who has her entire life been on the use of a pacemaker for her heart.

Is this the type of quality you speak?
One of the changes I personally do not like are drug induced changes due to massive amounts of hormones for athletes, such as human growth hormone, steroids, but frankly, these same drugs can have therapeutic benefit for people who are deficit of them. Sometimes the dividing line is not clear...such as in gender changes, or inducing ovulation for women who are older and want to have children. Those are societal issues, in which we take sides, and argue. One of the changes here in my state is the chemical castration of sex offenders in order to get parole, and yes, it is a moral issue, behavioral in nature, and it does make a change in their lives (although the psychological changes do not coincidentally take place). Another issue world wide that has gained prominence because of migration is Female Genital Mutilation (FGM), common in African, Middle East, and the Far East cultures. We recently had a case of it in my area.
So your question is a good one, but it is fraught with moral questions, and to me, the only way to tackle it is issue by issue.

Determining whether it is right or wrong to make changes to the qualities of humans is a subjective ethical question, and people may have different perspectives on this matter. Some may argue that enhancing or modifying human qualities through technologies like genetic engineering or advanced medical interventions can lead to improvements in health, intelligence, or longevity, benefiting individuals and society as a whole. They may see it as a way to address genetic defects or enhance desirable traits.

On the other hand, some ethical concerns arise regarding the potential consequences and implications of modifying human qualities. These concerns may include questions around inequality, discrimination, or the unintended consequences of altering natural diversity. Critics argue that attempting to engineer or control human qualities may lead to negative social, environmental, or psychological effects, and could potentially undermine human rights and individual autonomy.

Ultimately, the answer to whether it is right or wrong to make changes to human qualities depends on personal values, cultural norms, and societal discussions. It is essential to weigh the potential benefits against the potential risks and consider ethical principles such as autonomy, equality, and justice when discussing and making decisions about such matters.