List two ways in which a metabolic block can have phenotypic effects?
What do your text materials say?
I think I have one answer mutations? but what I am stumped if that is even correct
well at least u tried...lol...
Since this is not my area of expertise, I searched Google under the key words "'metabolic block' 'phenotypic effects'" to get these possible sources:
http://72.14.253.104/search?q=cache:Amq86s9d-bQJ:biologylessons.net/files/ASSoW/Unit2/111GeneticCode/5Mutation/Mutationsandmutagens.doc+%22metabolic+block%22+%22phenotypic+effects%22&hl=en&ct=clnk&cd=1&gl=us&client=safari
http://www.thestudentroom.co.uk/wiki/Revision:Genetics_and_Evolution
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http://www3.interscience.wiley.com/cgi-bin/summary/117869530/SUMMARY?CRETRY=1&SRETRY=0
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In the future, you can find the information you desire more quickly, if you use appropriate key words to do your own search.
I hope this helps. Thanks for asking.
To understand how a metabolic block can have phenotypic effects, let's first define what a metabolic block is. A metabolic block refers to a disruption in a specific step or pathway of a metabolic process. This disruption prevents the normal flow of metabolites and disrupts the production of essential molecules or energy within cells.
Here are two ways in which a metabolic block can have phenotypic effects:
1. Accumulation of toxic metabolites: In certain metabolic pathways, if there is a block at a specific step, the metabolites produced before the block may accumulate because they cannot be further processed. Some of these accumulated metabolites can be toxic to cells and tissues. For example, in phenylketonuria (PKU), there is a block in the pathway that breaks down the amino acid phenylalanine. As a result, phenylalanine builds up in the body, leading to the toxic accumulation of phenylalanine and its byproducts. This accumulation can cause phenotypic effects such as neurological damage, developmental delays, and intellectual disabilities.
2. Deficiency of essential molecules: Some metabolic blocks can impair the production of essential molecules that are required for normal physiological processes. For instance, in biotinidase deficiency, there is a block in the metabolism of biotin, a B-vitamin that is essential for various enzymatic reactions in the body. When this block occurs, the body is unable to produce sufficient amounts of biotin, leading to its deficiency. The phenotypic effects of biotinidase deficiency can include skin rashes, hair loss, neurological abnormalities, and impaired immune function, which are all consequences of the essential biotin deficiency.
In summary, a metabolic block can have phenotypic effects by causing the accumulation of toxic metabolites or by leading to deficiencies of essential molecules, both of which can negatively impact normal physiological processes.