posted by .

Which two ionization states of lysine are present at pH 7 in what and ratio? Show calculation

  • Biochemistry -

    To gret you started L-lysine has three pKa's: pKa1=2.20, pKa2=8.90 and pKa3=10.28.

    If we start below pH=2 the charge on the molecule is +2. At pH=7 which of the three groups are protonated?

Respond to this Question

First Name
School Subject
Your Answer

Similar Questions

  1. Biochemistry

    Can anyone help?? What are the Concentrations of the various ionic species of a 0.1 M solution of lysine at pH4?
  2. biochemistry

    A weak base has pKb = 9.25.. A. Calculate the % ionization at pH = 8.25 B. Calculate the % ionization at pH = 10.25 C. What is the pH when 50% of the weak base is ionized?
  3. Chemistry

    Lysine, an essential amino acid in the human body, contains C,H,O, and N. In one experiment, the complete combustion of 2.175g of lysine gave 3.94g CO2 and 1.89g H2O. In a separate experiment, 1.873 g of lysine gave 0.436 g NH3. (a) …
  4. biochemistry

    The R-group of histidine is a weak base with a pKb of 6.0. Calculate the percent ionization at pH 7.4. What is the net charge of the following amino acids (single letter codes used) at pH7.4?
  5. biochemistry

    calculate the isoelectric point of each of the following amino acids: glutamic acid, serine, histidine, lysine, tyrosine, and arginine
  6. biochemistry

    Trypsin can also hydrolyze N-alpha-benzoyl-L-lysine-p-nitroanilide. TrueFalse
  7. chemistry

    Lysine, an essential amino acid in the human body, contains C,H,O and N only. In an experiment, the complete combustion of 2.175 g lysine gave 3.94 g of CO2 and 1.89 g of H2O. In another reaction, the nitrogen content of 1.873 g of …
  8. chemistry

    ) Calculate the amount of unreacted aqueous ethanoic acid (CH3COOH(aq)) in the sample taken for titration with aqueous potassium hydroxide(KOH(aq)). Clearly show the steps in your calculation. (1 mark) (v) Hence calculate the amount …
  9. Chemistry

    Analytical Chemistry question: Find the pH and the concentration of each species of lysine in a solution of 0.0010 M lysine*HCL. I know that the pKAs of lysine are (1.77)(CO2H) 9.07 (-NH3) 10.82 ( -NH3) but I am not sure where to …
  10. Biochemistry

    All amino acids have two ionizable groups (an alpha-amino group with pKa~9.3, and an alpha-carboxyl group with pKa~2.2). Lysine also has an ionizable side-chain (R) with a pKa of 10.5. What percentage of the Lysine side chain is deprotonated …

More Similar Questions