....CH3.................O...........................
...__/......................||..........................
..// \\______N___C___CH___NH2.
..\==/.............|..................||….............
........\...........H…….......CH3………....
......CH3.............................................
i)one amine functional group and one amide functional group
ii) Draw an abbreviated structural formulae of the products of the complete hydrolysis of this compound. Identify any new functional groups in the products
iii) identify two examples of the atoms or groups in compund 3 that could be involved in it binding to receptor sites in the body via hydrogen bonding. give reasons why
i) From the given structure, we can identify one amine functional group and one amide functional group.
The amine functional group can be identified as NH2, which is bonded to a carbon atom.
The amide functional group can be identified as the carbonyl group (C=O), which is bonded to a nitrogen atom. In this case, the NH2 group is connected to the carbonyl carbon.
ii) To draw the structural formulas of the products of the complete hydrolysis of this compound, you will need to break the bonds between the nitrogen and carbon atoms in both the amine and amide functional groups.
After hydrolysis, the amine group (NH2) will be converted into ammonia (NH3) and a hydrogen ion (H+).
The amide group (C=O bonded to NH2) will be converted into a carboxylic acid group (COOH) and an amine group (NH2).
The final structural formulae will be:
CH3 CH3
...............||........... + ...................||
...........N—C—CH—NH2 + H2O → CH3
..............|................................. ||
..............H ................OH
In the first product, a new functional group, carboxylic acid (COOH), is formed. In the second product, a new functional group, alcohol (OH), is formed.
iii) To identify atoms or groups that could be involved in binding to receptor sites in the body via hydrogen bonding, we need to consider atoms with available hydrogen atoms and electronegative atoms that can act as hydrogen bond acceptors.
In the given compound, the amine functional group (NH2) can potentially act as both a hydrogen bond donor (with the hydrogen atom) and a hydrogen bond acceptor (with the lone pairs on the nitrogen atom). Therefore, the amine group could be involved in hydrogen bonding with receptor sites.
Another potential hydrogen bonding group is the carbonyl oxygen (C=O) in the amide functional group. Oxygen is electronegative and can act as a hydrogen bond acceptor. The carbonyl oxygen can form hydrogen bonds with hydrogen bond donors present on receptor sites.
Both the amine group and the carbonyl oxygen in the compound have the potential to form hydrogen bonds, making them good candidates for binding to receptor sites in the body via hydrogen bonding.